Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC 2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindoline-4-carboxylic acid | 1547163-38-1 | MFCD32063448 | 98.0% | 302.24 g·mol⁻¹ | C14H10N2O6 | 1 G
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Thalidomide acid is a carboxylic-acid-functionalized thalidomide analog used as an E3 ligase ligand in targeted protein degradation (PROTAC) research. Supplied as a powder for research use only, it serves as a building block for conjugation and linker attachment in chemical biology and medicinal chemistry workflows.
- Useful as an E3 ligase ligand for PROTAC development.
- Carboxylic acid functional group suitable for conjugation chemistry.
- High purity suitable for research applications.
- Powder form for ease of handling and storage.
- Characterized by CAS 1547163-38-1 and molecular weight 302.24 g·mol⁻¹.
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TARGETMOL CHEMICALS INC ANTITRYPANOSOMAL AGENT 2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei. purity: 100%
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Medchemexpress LLC GB-0895 1mg | 1mg
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GB-0895 is a human monoclonal antibody (mAb) targeting TSLP GB-0895 can be used in Asthma research Recommended isotype control Human IgG1 kappa Isotype Control (HY-P99001)[1]
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TARGETMOL CHEMICALS INC 4-CMTB 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38). purity: 99%
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Enzo Life Sciences H-1152 . dihydrochloride, (1mg), CAS Number: 45146-2-58-1
ROCK inhibitor. A cell permeable, highly specific, potent and ATP-competitive inhibitor of Rho kinase (ROCK) (Ki=1.6nM). Exhibits a much weaker affinity for other serine/threonine kinases (Ki=630nM for PKA, 9.27mM for PKC and 10.1mM for MLCK). More potent and selective than Y-27632 (Prod. No. ALX-270-333). Inhibits the phosphorylation of MARCKS in cells stimulated by lysophosphatidic acid. Inhibits EP3-stimulated NO formation. Prevents fragmentation of apoptotic cells. Relieves neuropathic pain. Alternative Name: H-1152P. 2HCl, (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine . 2HCl. Formula: C16H21N3O2S . 2HCl. MW: 319.4 . 73.0. CAS Number: 45146-2-58-1. Purity: ≥98% (TLC). Appearance: White to off-white solid. Solubility: Soluble in water. Long Term Storage: -20°C
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Medchemexpress LLC N3,3',N5-trimethyl-4'-{[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-... | 1373346-85-0 | 98.2% | 25MG
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N3,3',N5-trimethyl-4'-{[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-... | 1373346-85-0 | 98.2% | 25MG
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TARGETMOL CHEMICALS INC GPR34 RECEPTOR ANTAGONIS 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GPR34 receptor antagonist 2 (Tyrosine N-[(2E)-3-(4'-chloro[11'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-) is an anti-inflammatory agent. purity: 99%
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Apexbio Technology LLC Fluvastatin Sodium, 50mg. Cas: 93957-55-2 MFCD: MFCD00929076. HMG-CoA reductase inhibitor
Fluvastatin sodium is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase [1].Fluvastatin is a drug used to treat patients with hypercholesterolaemia. Other sizes are available. Please inqury us for quote.
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Cayman Chemical 3-(3-Hydroxyphenyl)-3-hydroxypropanoic Acid, Purity: ≥98%, CAS: 3247-75-4, 5 mg
A urinary metabolite
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Medchemexpress LLC hVEGF-IN-1 | 1637443-98-1 | 99.3% | 581.75 g/mol | C34H43N7O2 | 100 MG
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hVEGF-IN-1 is a quinazoline-derived small-molecule research reagent that inhibits VEGF-A expression by binding G-rich sequences within the IRES-A element and destabilizing G-quadruplex structures. It has been reported to reduce VEGF-A protein levels, hinder tumor cell migration, and suppress tumor growth in cellular assays.
- Binds G-rich IRES-A sequence and destabilizes G-quadruplex structures.
- Reduces VEGF-A protein expression in cellular assays.
- Inhibits tumor cell migration and growth in vitro.
- High chemical purity suitable for research applications.
- Available in multiple solid and solution package sizes for experimental flexibility.
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Medchemexpress LLC Apcin-a | 1683617-62-0 | 98.0% | C10H14Cl3N5O2 | 10MG
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Apcin-A is a small-molecule inhibitor that selectively targets the cell division cycle protein Cdc20. It competitively binds the D-box pocket of Cdc20 to inhibit APC/C-Cdc20-mediated substrate ubiquitination, blocking binding of proteins such as securin and cyclin B1 and interfering with anaphase initiation. Supplied as a research reagent for cellular and biochemical studies.
- Selective Cdc20 inhibition for mitotic regulation studies.
- Derivative of apcin that blocks substrate ubiquitination.
- High purity (98.0%) for reproducible results.
- Soluble in DMSO at 100 mg/mL for convenient stock solutions.
- Solid, off-white to yellow appearance; stable under recommended storage.
- Intended for research use only; not for human or clinical use.
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TARGETMOL CHEMICALS INC OU749 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. OU749 is a (gamma)-glutamyl transferase (GGT) inhibitor with an intrinsic Ki of 17.6 uM. purity: 99%
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Cayman Chemical RSM-932A, Purity: ≥95%, CAS: 850807-63-5, 1 mg
A selective inhibitor of CHOKα (IC50s = 1 and >50 μM for CHOKα and β, respectively); induces apoptosis via CHOP signaling and ER stress in MDA-MB-231, MCF-7, SW620, and H460 cancer cells; inhibits the growth of HT-29 colon cancer cells in vitro (IC50 = 1.15 μM) and in vivo in a mouse xenograft model (ED50 = 7.5 mg/kg)
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Cayman Chemical GW 405833, Purity: ≥98%, CAS: 180002-83-9, 1 mg
A partial agonist of CB2 receptors (EC50 = 0.65 nM); demonstrates anti-inflammatory and antihyperalgesic properties in animal models of inflammation and pain
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Cayman Chemical Erteberel, Purity: ≥98%, CAS: 533884-09-2, 10 mg
An ERβ agonist; selective for ERβ over ERα in reporter assays using PC3 cells expressing the human receptors (EC50s = 0.66 and 19.4 nM, respectively); induces apoptosis and cell cycle arrest at the G2/M phase in U87MG and U251 cells at 5 µM; enhances cisplatin-, lomustine-, or bleomycin-induced cytotoxicity in U251 cells at 1 µM; reduces tumor growth in a U251 orthotopic model of glioblastoma in ovariectomized mice at 5 mg/kg; decreases prostate weight in a mouse model of BPH at 0.01, 0.025, and 0.05 mg/kg
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